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The risk that you will develop breathing problems may be higher if you are an older adult or are weak or malnourished due to disease. Also tell your doctor if you have or have ever had lung disease such as chronic obstructive pulmonary disease (COPD a group of lung diseases that includes chronic bronchitis and emphysema), a head injury, or any condition that increases the amount of pressure in your brain. Your doctor will probably tell you not to take methadone. Tell your doctor if you have or have ever had slowed breathing or asthma. Your doctor will monitor you carefully during your treatment. Methadone may cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased. Substance Abuse and Mental Health Services Administration (SAMHSA) National Helpline at 1-800-662-HELP. Talk to your healthcare provider immediately and ask for guidance if you think that you have an opioid addiction or call the U.S. There is a greater risk that you will overuse methadone if you have or have ever had any of these conditions. Tell your doctor if you or anyone in your family drinks or has ever drunk large amounts of alcohol, uses or has ever used street drugs, or has overused prescription medications, or if you have or have ever had depression or another mental illness. While taking methadone, discuss with your healthcare provider your pain treatment goals, length of treatment, and other ways to manage your pain. Do not take a larger dose, take it more often, or take it for a longer period of time or in a different way than prescribed by your doctor.